An update to Twemoji began rolling out to users on 2019-11-06 and was added to the open source repository on 2019-11-13. This release gave a gender-inclusive appearance to most human emojis when a gender isn't specified.

Note: this did not add support for additional gender-neutral sequences approved in Emoji 12.1 - instead it changed the appearance of existing neutral emojis.

Discord updated its emoji support to Twemoji 12.1.4 in November 2019, in the first emoji update on the platform since 2016.